Certain medications can make your kidneys work less well if they are taken when you are ill. In severe cases this can lead to kidney failure which could have been avoided.
Which Medications Should I pause?
ACE inhibitors - these end in ‘pril’ – eg ramipril, perindopril, lisinopril ARBs - these end in ‘sartan’ – eg candesartan, losartan, valsartan NSAIDs - ibuprofen, naproxen, diclofenac (use just paracetamol for fever if possible) Metformin - also known as glucophage, Sukkarto etc SGL2 inhibitors - these end in ‘gliflozin’- eg dapagliflozin, empaflagozin, cangliflozin Diuretics (water tablets) - e.g. furosemide, bumetanide, bendroflumethazide, indapamide
Please be careful. Some medications a supplied as a brand name but contain these drugs. If you are unsure ask your pharmacist.
When should pause them?
Any dehydrating illness, e.g. Significant vomiting or diarrhoea (more than 12-24h) Severe fevers / sweats Any other illness that is stopping you taking in a good volume of fluids
When should I re-start them?
It is important to RESTART your medication after a day or two when you feel better Please discuss with your GP if you are unwell for more than 48h
Patients often worry about stopping ACE inhibitors or ARBs that are used for controlling blood pressure. Stopping them for a few days if needed will NOT alter their long term benefit.
If you are worried about this, or need further advice about your medications please discuss with your pharmacist